PUBLICATIONS

Chung, M. C., Mendez-Gomez, H. R., Soni, D., McGinley, R., Zacharia, A., Ashbrook, J., Stover, B., Grippin, A. J., Sayour, E. J., & Guan, J. (2025). Multi-Step Assembly of an RNA-Liposome Nanoparticle Formulation Revealed by Real-Time, Single-Particle Quantitative Imaging. Advanced science (Weinheim, Baden-Wurttemberg, Germany), e2414305.
Narayan, O. P., Dong, J., Huang, M., Chen, L., Liu, L., Nguyen, V., Dozic, A. V., Liu, X., Wang, H., Yin, Q., Tang, X., & Guan, J. (2025). Reversible light-responsive protein hydrogel for on-demand cell encapsulation and release. Acta biomaterialia, 193, 202–214.
Gonzalez-Martinez, D., Roth, L., Mumford, T. R., Guan, J., Le, A., Doebele, R. C., Huang, B., Tulpule, A., Niewiadomska-Bugaj, M., Bivona, T. G., & Bugaj, L. J. (2024). Oncogenic EML4-ALK assemblies suppress growth factor perception and modulate drug tolerance. Nature communications, 15(1), 9473
Mendez-Gomez, H. R., DeVries, A., Castillo, P., von Roemeling, C., Qdaisat, S., Stover, B. D., Xie, C., Weidert, F., Zhao, C., Moor, R., Liu, R., Soni, D., Ogando-Rivas, E., Chardon-Robles, J., McGuiness, J., Zhang, D., Chung, M. C., Marconi, C., Michel, S., Barpujari, A., … Sayour, E. J. (2024). RNA aggregates harness the danger response for potent cancer immunotherapy. Cell, 187(10), 2521–2535.e21.
Haderk, F., Chou, Y. T., Cech, L., Fernández-Méndez, C., Yu, J., Olivas, V., Meraz, I. M., Barbosa Rabago, D., Kerr, D. L., Gomez, C., Allegakoen, D. V., Guan, J., Shah, K. N., Herrington, K. A., Gbenedio, O. M., Nanjo, S., Majidi, M., Tamaki, W., Pourmoghadam, Y. K., Rotow, J. K., … Bivona, T. G. (2024). Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer. Nature communications, 15(1), 3741.
Mumford, T. R., Rae, D., Brackhahn, E., Idris, A., Gonzalez-Martinez, D., Pal, A. A., Chung, M. C., Guan, J., Rhoades, E., & Bugaj, L. J. (2024). Simple visualization of submicroscopic protein clusters with a phase-separation-based fluorescent reporter. Cell systems, 15(2), 166–179.e7.
Huang, M., Wang, H., Mackey, C., Chung, M. C., Guan, J., Zheng, G., Roy, A., Xie, M., Vulpe, C., & Tang, X. (2023). YAP at the Crossroads of Biomechanics and Drug Resistance in Human Cancer. International journal of molecular sciences, 24(15), 12491.
Luo, Q., Zhang, J., Huang, M., Lin, G., Tanaka, M., Lepler, S., Guan, J., Siemann, D., & Tang, X. (2022). Automatic Multi-functional Integration Program (AMFIP) towards all-optical mechano-electrophysiology interrogation. PloS one, 17(7), e0266098.
Huang, M., Wang, H., Delgado, A. A., Reid, T. A., Long, J., Wang, S., Sussman, H., Guan, J., Yamaguchi, H., & Tang, X. (2022). Combining 3D Magnetic Force Actuator and Multi-Functional Fluorescence Imaging to Study Nucleus Mechanobiology. Journal of visualized experiments : JoVE, (185), 10.3791/64098.
Ziegler, T.M., Chung, M.C., Narayan, O. P. & Guan, J*. (2021). Protein phase separation: Physical
models and phase-separation-mediated cancer signaling. Advances in Physics: X. 6, 1936638.
(*corresponding author) LINK
Tulpule, A.*, Guan, J.*, Neel, D.*, Allegakoen, H.R., Lin, Y.P., Brown, D., Chou, Y.T., Heslin, A., Chatterjee, N., Perati,
S., Menon, S., Nguyen, T., Debnath, J., Ramirez, A.D., Shi, X., Yang, B., Feng, S., Makhija, S., Huang, B. &
Bivona, T.G. (2021). Kinase-mediated RAS Signaling via membraneless cytoplasmic protein granules. Cell
184, 2649-2664. (*co-first author) LINK
Alexander, J., Guan, J., Huang, B., Lomvardas, S. & Weiner, O.D. (2019) Live-cell imaging reveals enhancer-
dependent Sox2 transcription in the absence of enhancer proximity. eLife 8, e41769. LINK
Percharde, M., Lin, C.J., Yin, Y., Guan, J., Peixoto, G.A., Bulut-Karslioglu, A., Biechele, S., Huang, B., Shen, X. &
Ramalho-Santos, M. (2018). A LINE1-Nucleolin partnership regulates early development and ESC identity.
Cell 174, 391. LINK
Chow, T., Shi, X., Wei, J., Guan, J., Stadler, G., Huang, B., E. & Blackburn, E.H. (2018). Local enrichment of
HP1alpha at telomeres alters their structure and regulation of telomere protection.
Nature Communications 9, 3583. LINK
Guan, J., Chen, K., Jee, A.Y. & Granick, S. (2018). DNA molecules deviate from shortest trajectory when driven
through hydrogel. Journal of Chemical Physics 149, 163331. LINK
Guan, J., Liu, H., Shi, X., Feng, S. & Huang, B. (2017). Tracking multiple genomic elements using correlative
CRISPR imaging and sequential DNA FISH. Biophysical Journal 112, 1077. Highlighted as “New and
Notable” with accompanying Perspective article. LINK
Chen, B.*, Guan, J.* & Huang, B.* (2016). Imaging specific genomic DNA in living cells. Annual Review
Biophysics 45, 1. (*co-corresponding author) LINK
Guan, J., Wang, B. & Granick, S. (2014). Even hard-sphere colloidal suspensions display Fickian yet non-
Gaussian diffusion. ACS Nano 8, 3331. LINK
Guan, J., Wang, B., Bae, S.C. & Granick, S. (2013). Modular stitching to image single-molecule DNA transport.
Journal of American Chemical Society 135, 6006. LINK
Yu, C., Guan, J., Chen, K., Bae, S.C. & Granick, S. (2013). Single-molecule observation of long jumps in polymer
adsorption. ACS Nano 7, 9735. LINK
Chen, K., Wang, B., Guan, J. & Granick, S. (2013). Diagnosing heterogeneous dynamics in single
molecule/particle trajectories with multiscale wavelets. ACS Nano 7, 8634. Highlighted by the issue with
accompanying Perspective article. LINK
Guan, J., Wang, B. & Granick, S. (2011). Automated single molecule tracking of DNA shape. Langmuir 27, 6149
LINK
Granick, S., Bae, S.C., Wang, B., Kumar, S., Guan, J., Yu, C., Chen, K. & Kuo, J. (2010) Single-molecule methods in
polymer science. Journal of Polymer Science Part B Polymer Physics 48, 2542. LINK
Ye, X., Fei, J., Guan, J., Zhou, X. & Zhang, G. (2010). Dispersion of polystyrene inside polystyrene-b-poly (N-
isopropylacrylamide) micelles in water. Journal of Polymer Science Part B Polymer Physics. 48, 749. LINK
Wang, B., Guan, J., Anthony, S.M., Bae, S.C., Schweizer, K.S. & Granick, S. (2010). Confining potential when a
biopolymer filament reptates. Physics Review Lett. 104, 118301. Marked as editor’s suggestions. LINK
Marre, S., Park, J., Rempel, J., Guan, J., Bawendi, M.G. & Jensen, K.F. (2008). Supercritical continuous microflow
synthesis of narrow size distribution quantum dots . Advanced Materials 20, 4830. LINK